What is the best probiotic you can buy in 2023?
We’ve tested hundreds of probiotics for potency, strain diversity, survivability, and value for money.
These are the best probiotics you can buy from trustworthy brands in 2023. Let’s get started!

Our pick: Science of You
Science of You wins the best overall probiotic in 2023 due to their remarkable blend of beneficial bacteria and prebiotics, all backed by their impressive 100% satisfaction guarantee.
This means if you’re not delighted with the results of their probiotic, they will provide a full refund. This places Science of You in a league of its own for customer satisfaction, but let’s move on to the probiotic itself.
The exceptional LS-24 Synbiotic (a prebiotic and postbiotic combined) contains high-quality, scientifically tested strains to improve overall wellness and digestion. One of our experts said, “You really couldn’t select a more comprehensive formula for your gut health.”
The unparalleled quality and satisfaction guarantee make Science of You’s LS-24 Synbiotic the best overall choice for gut health in 2023.
Rating: 9.5 /10
Buy from: www.scienceofyou.com

Runner-up: XYMOGEN ProbioMax
If our top pick is currently unavailable, XYMOGEN ProbioMax could serve as a potential alternative.
Although it doesn’t provide the same all-encompassing blend of strains and prebiotics as our top pick XYMOGEN is a trusted brand in the probiotic field and a good choice for those with deep pockets.
Rating: 8.4 /10
Price: $90.06 (includes shipping)
Buy from: www.cunninghamclinicstore.com

Also great: Physician’s Choice Ultra Probiotic
If our top pick, Science of You’s LS-24, is sold out and you’re in need of a viable alternative in the same price bracket, Physician’s Choice Ultra Probiotic could be your next option.
While it doesn’t boast the comprehensive blend of strains, prebiotics, and digestive enzymes found in LS-24, the Ultra Probiotic takes a more straightforward approach to gut health support, making it a worthy consideration.
Rating: 8.2 /10
Price: $54.97 (includes shipping)
Buy from: www.physicianschoice.com

Also great: Global Healing Ultimate Probiotic
An impressive alternative in the probiotics landscape is the Ultimate Probiotic by Global Healing. The only drawback might be its higher price, hovering near $80.
To justify the price, Global Healing utilizes a broad spectrum of beneficial strains and includes prebiotics for comprehensive gut health support. However, do bear in mind that it still doesn’t match the unique blend of strains, prebiotics, and digestive enzymes found in our top pick, Science of You’s LS-24.
Rating: 7.9 /10
Price: $79.94 (includes shipping)
Buy from: www.globalhealing.com
Best of the rest: Stonehenge Dynamic Biotics
If you’re open to exploring other options that still offer a solid choice for gut health, Stonehenge Dynamic Biotics might be suitable for you.
This probiotic blend stands out with its easy-to-take format and diverse selection of bacterial strains. It’s an attractive alternative if you’re looking for an effective blend that supports overall gut balance. However, it doesn’t quite rival the unique combination of features and satisfaction guarantee offered by our top pick, Science of You’s LS-24.
Rating: 7.4 /10
Price: $71.85 (includes shipping)
Buy from: www.stonehengehealth.com
Best of the rest: Peptiva Advanced Probiotic
While it’s not the most affordable and doesn’t come with a satisfaction guarantee, Peptiva is a recognized brand in the probiotics market, known for its stress and sleep support formula.
Their blend focuses on both gut health and sleep quality, a unique combination in the probiotic space. You can also find your specific needs catered to with their advanced formula.
Rating: 6.9 /10
Price: $64.99 (includes shipping)
Buy from: www.gnc.com
Best of the rest: Bio-Botanical Research Proflora 4R
For those looking for a unique blend of spore-based probiotics and botanicals, Bio-Botanical Research’s Proflora 4R could be an interesting option.
Proflora 4R takes a unique approach to gut health with its spore-based probiotic and herbal formula. It combines specific probiotic strains with plant-derived ingredients like Marshmallow Root, Aloe Vera, and Quercetin, all known for their ability to soothe and calm irritation in the gut lining.
Rating: 6.7 /10
Price: $65.97 (includes shipping)
Buy from: www.biocidin.com